Phenylboronic Acid CAS 98-80-6: Specifications, Applications, and Buying Guide

Phenylboronic acid CAS 98-80-6 is an organoboron compound widely used as a synthetic building block, especially in Suzuki–Miyaura cross-coupling and related carbon–carbon bond-forming reactions. Its molecular formula is C₆H₇BO₂, and its molecular weight is approximately 121.93 g/mol. For B2B buyers, the most important purchasing factors are identity, assay, impurity profile, packaging, documentation, and supply consistency rather than price alone.

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At Maison Chemical, I support pharmaceutical, agrochemical, specialty chemical, and research-industry buyers with Phenylboronic acid sourcing and export coordination. This guide explains the material’s core specifications, typical applications, selection criteria, and the questions buyers should ask before placing a purchase order.

Who This Guide Is For

This guide is intended for procurement teams, process chemists, R&D laboratories, contract manufacturers, and distributors evaluating Phenylboronic acid CAS 98-80-6. It is also useful for buyers comparing suppliers for pilot-scale development, routine manufacturing, or international shipment. The appropriate specification depends on the intended reaction, process scale, downstream purification requirements, and internal quality standards.

I recommend using this information as a purchasing framework rather than as a substitute for a project-specific specification. Buyers should always confirm the current certificate of analysis, safety documentation, packaging options, and applicable transport requirements with the supplier before ordering.

Basic Chemical Context and Key Specifications

Phenylboronic acid contains a phenyl group attached to a boronic acid functional group. The boronic acid moiety can participate in reversible interactions with certain diols and can also serve as a useful coupling partner in palladium-catalyzed cross-coupling chemistry. These properties make the compound relevant to synthetic routes where controlled carbon–carbon bond construction is required.

Commercial grades can differ in assay, water content, residual solvents, trace metals, and other related substances. A buyer should therefore avoid evaluating a supplier only by the product name and CAS number. The batch-specific certificate of analysis is the more relevant document for confirming whether the offered material fits a particular application.

Material Options and Grade Selection

Standard research and development grade

For laboratory screening and route development, buyers often require a reliable material with documented assay and a practical package size. This grade may be suitable when the process is still being optimized and the final impurity requirements have not yet been established. I recommend confirming whether the supplier can provide chromatographic purity, water content, and a representative batch specification.

Higher-purity process material

Process development and manufacturing applications may require tighter control of organic impurities, inorganic residues, moisture, or trace metals. Higher-purity material can be important when impurities affect catalyst performance, crystallization, reaction conversion, or downstream purification. The correct target should be defined by the buyer’s process data rather than by a generic “high purity” description.

Custom specification or documentation package

Some buyers need additional documents such as a specification sheet, certificate of analysis, safety data sheet, packing list, origin information, or batch traceability records. In regulated or quality-controlled supply chains, documentation expectations should be agreed before production or shipment. Maison Chemical can review these requirements during quotation so that the proposed material and paperwork are aligned with the purchasing workflow.

Application Matching: Where Phenylboronic Acid Is Used

The best-known application is Suzuki–Miyaura coupling, in which aryl or vinyl boronic acids react with suitable electrophilic partners under appropriate catalytic and basic conditions. Phenylboronic acid is commonly selected when a phenyl group is needed in the target structure. Actual performance depends on the reaction system, catalyst, solvent, base, temperature, substrate, and purification method.

Pharmaceutical and medicinal chemistry teams use Phenylboronic acid as a building block or intermediate input during the preparation of more complex aromatic compounds. It may be used in discovery chemistry, process development, or intermediate synthesis, although the required grade and documentation can vary substantially between these stages. Buyers should provide information about whether the material is for exploratory research or commercial production.

The compound can also be relevant to agrochemical intermediate synthesis, specialty organic materials, and analytical or academic research. Boronic acid functionality is additionally studied in molecular recognition and sensor-related chemistry because it can interact with selected diol-containing structures. These research uses do not eliminate the need for chemical compatibility, handling controls, and application-specific validation.

Buyer Selection Framework

1. Confirm identity and specification

Start with the exact product name, CAS number, molecular formula, target assay, and acceptable impurity limits. Ask for a current certificate of analysis rather than relying only on a catalog statement. If the material will enter a validated process, compare the supplier’s specification with your internal raw-material standard before approval.

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2. Review physical and chemical quality indicators

Important indicators may include assay by an appropriate analytical method, related substances, water content, residual solvents, elemental or trace-metal information, and appearance. Not every project needs every test, so buyers should identify the attributes that can affect their reaction or final product. When moisture sensitivity or catalyst poisoning is a concern, those parameters deserve particular attention.

3. Match packaging to quantity and storage

Packaging should protect the solid from contamination, excessive humidity, and mechanical damage during handling and transport. For small laboratory orders, a compact inner container may be convenient, while larger quantities may require additional protective packaging and clear lot identification. The buyer should confirm net weight, container material, labeling, storage guidance, and whether repacking is performed before shipment.

4. Evaluate commercial terms

Price should be reviewed together with minimum order quantity, sample availability, production lead time, payment terms, shipping method, and documentation support. A lower unit price may not be commercially attractive if it requires an unsuitable quantity or creates long approval delays. For international procurement, buyers should also confirm the shipping destination, customs information, and the documents required by their import process.

Pricing, MOQ, and Lead-Time Considerations

Phenylboronic acid pricing is influenced by assay, order quantity, packaging, market conditions, testing requirements, and destination. Because these factors change, I recommend requesting a quotation based on a defined quantity and specification instead of using an old reference price. A clear request helps the supplier return a more useful comparison between laboratory, pilot, and production quantities.

Minimum order quantity can differ by grade and whether the material is available from stock or must be scheduled for production. Lead time may also depend on quality-control testing, packaging preparation, export documentation, and the selected transport route. Buyers with fixed manufacturing dates should communicate the required delivery window at the quotation stage and request confirmation before issuing a purchase order.

Supplier Evaluation Checklist

• Does the supplier identify the product consistently as Phenylboronic acid CAS 98-80-6?
• Can the supplier provide a batch-specific certificate of analysis?
• Are assay, related substances, moisture, and other critical parameters clearly defined?
• Can the supplier support the required package size and order quantity?
• Are storage, labeling, safety data, and shipping documents available for review?
• Can the supplier explain the expected production and delivery schedule?
• Is there a clear process for handling samples, technical questions, and nonconformities?
• Can the supplier support repeat orders with consistent specifications and lot traceability?

I also suggest requesting a sample or pre-shipment document review when the material will be used in a sensitive reaction. A supplier should be able to explain which tests are routine, which are available by request, and how deviations are managed. This approach gives the buyer a more realistic view of supply capability than a simple product listing.

Common Purchasing Mistakes to Avoid

One common mistake is selecting solely on the basis of the lowest quoted price. This can create additional costs if the purity profile, moisture level, packaging, or delivery schedule does not match the process. Another mistake is failing to distinguish a research-grade requirement from a manufacturing-grade requirement, which may lead to unnecessary testing or inadequate controls.

Buyers should also avoid approving a supplier without confirming the actual shipment documents and batch information. Product identity, lot number, net weight, and certificate details should be consistent across the order and delivery paperwork. If a project is time-sensitive, waiting until after the purchase order to discuss lead time or export requirements can introduce avoidable delays.

How Maison Chemical Supports B2B Buyers

At Maison Chemical, I focus on clarifying the buyer’s application, quantity, quality requirements, destination, and documentation expectations before recommending a supply option. We can discuss standard versus tighter specifications, sample needs, packaging preferences, and the information required for internal supplier approval. This consultation is especially useful when the buyer is comparing several offers with different purity and service conditions.

Our support is intended for pharmaceutical intermediate procurement, specialty chemical sourcing, research supply, and export-oriented purchasing. Availability, MOQ, price, and lead time should be confirmed for each inquiry because they depend on the requested specification and order details. We do not treat a generic product description as a substitute for batch-specific commercial information.

Summary and Next Steps

Phenylboronic acid CAS 98-80-6 is a versatile organoboron building block with a molecular weight of approximately 121.93 g/mol and broad relevance to aromatic synthesis. The right buying decision depends on more than identity: assay, impurity profile, moisture, packaging, documentation, MOQ, lead time, and application fit all matter. For a dependable procurement process, buyers should define their internal specification first and then compare suppliers against the same criteria.

To begin, send Maison Chemical your required quantity, target specification, application stage, destination, packaging preference, and documentation needs. I can then help you evaluate the appropriate supply option and prepare a practical quotation for Phenylboronic acid CAS 98-80-6. This structured approach supports clearer technical review, more predictable purchasing, and better long-term supply planning.

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