2-Fluoro-4-(trifluoromethyl)phenylboronic Acid CAS 503309-11-3: Uses, Specifications, and B2B Purchasing Guide

2-Fluoro-4-(trifluoromethyl)phenylboronic acid, CAS 503309-11-3, is an arylboronic acid used as a building block in carbon–carbon bond formation, particularly Suzuki–Miyaura coupling. Its fluorinated aromatic ring can be incorporated into more complex molecules by coupling it with a suitable aryl or vinyl electrophile. Buyers should confirm identity, assay, impurity profile, packaging, and current availability against their project requirements before placing an order. This guide explains the compound’s role, how to assess specifications, and what to clarify with a B2B supplier such as Maison Chemical.

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Key Takeaways

• CAS 503309-11-3 identifies the requested fluorinated arylboronic acid; verify the CAS number and chemical name across the quotation, label, and accompanying documentation.
• The compound is a potential coupling partner for synthesis, but reaction suitability depends on the substrate, catalyst system, and process conditions.
• Use a project-specific specification rather than assuming that a quoted purity, test method, package size, or lead time is universally available.
• Ask Maison Chemical to confirm the current batch details, documentation, packaging, and commercial terms before committing to a purchase.

Who This Guide Is For

This guide is intended for procurement teams, process chemists, medicinal chemistry groups, and chemical distributors evaluating CAS 503309-11-3. It is useful when you need to compare supplier quotations or translate a laboratory requirement into a purchasing specification. It can also help project teams identify questions to resolve before ordering a sample or production quantity. It does not replace an application-specific risk assessment or review of the supplier’s current product documents.

Compound Context and Core Function

What the boronic acid contributes

The compound contains an aromatic carbon–boron bond and two fluorinated substituents: a ring-bound fluorine and a trifluoromethyl group. In suitable reaction systems, the boronic acid group can participate in cross-coupling to form a new carbon–carbon bond. This makes the material a synthetic intermediate rather than a finished pharmaceutical ingredient or a standalone performance chemical. Its usefulness depends on whether the resulting substituted aromatic unit fits the target molecule and route.

As a structure-based reference, the molecular formula is C₇H₅BF₄O₂, with a calculated molecular weight of approximately 207.92 g/mol. On that basis, 1 mmol corresponds to about 207.92 mg at 100% assay; the mass used in a real reaction should account for the batch assay and the method used to report it. These calculated values are useful for checking order documents and planning stoichiometry, but they do not substitute for batch-specific analytical data.

Uses and Application Matching

Synthetic research and route development

A common reason to evaluate this material is to introduce its fluorinated aryl group into a larger structure through Suzuki–Miyaura coupling. The coupling partner may be an appropriate aryl or vinyl halide or another compatible electrophile, subject to the selected reaction design. The substrate, catalyst, base, solvent, water content, and temperature can all affect conversion and impurity formation. There is no single set of conditions that can be assumed to work for every target molecule.

In pharmaceutical and fine-chemical research, the material may be considered during synthesis of candidate compounds or intermediates. That description refers to its possible role in a synthetic route; it does not establish regulatory status, suitability for a particular drug, or acceptance in a validated manufacturing process. Before scale-up, project teams should assess reaction performance, residual impurities, work-up, and the handling requirements defined by their own procedures. For regulated applications, supplier documentation and internal qualification requirements should be reviewed together.

Specifications and Material Options

Commercial specifications should be confirmed for the specific lot being offered. A product name and CAS number establish the requested identity but do not, by themselves, demonstrate the assay, water content, impurity profile, or shelf life of a particular batch. Ask the supplier to state which parameters are routinely tested and which can be reported only by request. Where a parameter is important to your process, put it in the purchase specification rather than relying on an informal assumption.

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If your internal specification calls for a purity target such as ≥98%, treat that figure as a buyer-defined requirement to verify with the supplier, not as a claim about every available lot. The analytical method should also be agreed where results will determine acceptance, since values from different methods or reporting conventions may not be directly comparable. Request the batch’s certificate of analysis when available and check that its lot number matches the supplied container. Follow the current safety data sheet and site procedures for storage and handling.

How to Select a Grade and Supplier

Build a project-specific selection framework

1. Confirm the identity. Match the CAS number, chemical name, and structure in your internal record with the supplier’s quotation and product documentation.
2. Set acceptance criteria. Define the assay, test method, impurity limits, and any additional documentation your quality system requires.
3. Match quantity to the project stage. Request a suitable pack size for feasibility work, route development, or planned scale-up, and confirm the supplier’s actual packaging options.
4. Review logistics and handling. Confirm packaging configuration, shipping destination, applicable safety documents, and any handling or transport requirements relevant to your operation.
5. Assess continuity needs. For repeat orders, ask how batch availability, lead-time estimates, and change notification can be managed. Treat these as items to confirm rather than guaranteed commitments.

For early-stage work, a smaller quantity may reduce inventory exposure while chemistry is being evaluated, if the supplier can offer it. For a planned campaign, procurement should compare the required quantity with confirmed stock or production timing and include an appropriate allowance for analytical testing and process losses. Avoid extrapolating a laboratory result directly to a larger scale without route-specific evaluation. Changes in reaction scale can affect mixing, heat transfer, work-up, and impurity control.

Pricing, MOQ, and Lead Time

The price for CAS 503309-11-3 can vary with order quantity, requested specification, packaging, destination, and availability at the time of inquiry. Minimum order quantity and lead time are commercial details that should be confirmed in a current quotation rather than inferred from an old listing or a general market assumption. If you need a specific delivery date, provide the destination and required quantity when requesting a quote. Ask whether the estimate refers to stock ready for dispatch or material that must be scheduled.

To support a useful comparison, request quotations on the same basis: quantity, purity requirement, packaging, documentation, shipping terms, and delivery destination. A lower quoted unit price may not represent the best purchasing fit if the offered specification or documentation does not meet your acceptance criteria. Conversely, a broader specification may be adequate for exploratory work when your technical team approves it. Confirm all critical terms in writing before issuing a purchase order.

Supplier Evaluation Checklist

Questions to ask before ordering

• Can you confirm the product identity as 2-Fluoro-4-(trifluoromethyl)phenylboronic acid, CAS 503309-11-3?
• What assay or purity is offered for the quoted lot, and which analytical method is used?
• Can you provide a lot-specific certificate of analysis and the current safety data sheet?
• What package sizes, minimum order quantity, and current lead-time estimate are available?
• Can you confirm the shipping terms, destination-specific requirements, and any documentation needed for import or receiving?
• For repeat demand, what availability and batch-documentation information can be provided for future orders?

Maison Chemical can review these requirements with B2B buyers and confirm the product, available lot information, packaging, and quotation terms for the requested order. Share your target specification, quantity, destination, and documentation needs so the inquiry can be assessed against the current offer. Any requested assay, delivery schedule, or special packaging should be explicitly confirmed before purchase. This keeps technical and commercial expectations aligned.

Conclusion and Next Steps

2-Fluoro-4-(trifluoromethyl)phenylboronic acid, CAS 503309-11-3, is a fluorinated arylboronic acid that can serve as a coupling building block in suitable synthetic routes. Its calculated molecular weight is approximately 207.92 g/mol, while assay, impurity profile, packaging, availability, and lead time must be confirmed for the specific lot. To move forward, define your application and acceptance criteria, then request a current quotation and the relevant batch documentation from Maison Chemical. This provides a practical basis for deciding whether the offered material fits your project and purchasing requirements.

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